lidocaine

商品名(trade name)
藥理作用(Pharmacological Effects)	[minimal effect on Vmax, shorten APD-->ECG can see QT interval shorten [block I type Na+ channels: prolong ERP [heart [[Automaticity [[[SA Node [[[[no effect [[[Purkinje fibers [[[[If effect decrease [[Excitability [[[background Na+ i Ca2+ currents * Conductivity: no effect in normal tissue, but variable in abnormal tissue (ischemia: , strech: ) APD=action potential duration
用量與用法(Dosage and Usage)	usage ]IM ]IV ]no per os: high 1st pass effect
適應症(Indications)	{Ventricular arrhythmia:ex: digitalis, cardiac surgery or MI induction/ICU
副作用(Side effect)	}Agitation }convulsion }drowsiness }coma
禁忌/交互作用(Contraindications / interaction)

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