Sunday, October 20, 2013

nonketotic hyperosmolar state, NKHS(非酮酸性高滲透壓狀態)

症狀/併發症(symptom/complication)
@polyuria: glucose resorption is not fast enough than excretion
@thirst

病因(etiology)
|insulin deficiency and |inadequate fluid uptake
|ischemia
|iatrogenic
|infection
|intoxication
檢查/準則(examination/criteria)
#decreased GFR
#blood sugar>600 mg/dl
#arterial pH>7.3
#bicarbonate>15 mEq/L
#osmolality >320 mOsm/Kg H2O
#ketone bodies is a little high or normal
治療(treatment)

鑑別診斷(Differential Diagnosis)
%%do not nausea and vomiting
%%do not have abdomen pain
%%do not present Kussmaul respiration (DKA patient)
%%ketonemia is rare
流行病學(Epidemiology)
+usually occur in type II diabetes mellitus(第二型糖尿病)
+more common in elderly
+hard to access to water
New name is hyperosmolar hyperglycemic state, HHS(高滲透壓高血糖狀態)
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