症狀/併發症(symptom/complication) | @ low bone mass @microarchitectural deterioration @increase in fracture risk |
病因(etiology) | class |primary osteoporosis ||decrease bone mass in postmenopausal women (postmenopausal osteoporosis) ||older men and women (senile osteoporosis) |secondary osteoporosis ||loss of bone mass resulted from other clinical disorder |
檢查/準則(examination/criteria) | #vertebrae is the most incidence rate of body, but sometimes influenced by arteriosclerosis #T score: BMD is compared with 25-year-old Caucasian women ##Normal: T scores fall less than -1 SD ##Osteopenia: T score fall between -1 and -2.5 SD ##Osteoporosis: T score fall more than -2.5 SD |
治療(treatment) | $Non-pharmacologic $$do exercise $$Maintain nutrition status $$Prevention from trauma $Medication $$Anti-resorptive agent: do not improve calcium absorption, but block bone loss $$$Calcium: 1500 mg/day (Milk contain about 1 mg calcium /ml) $$$Vitamin D: 400 - 800 IU/D with adequate calcium intake $$$Estrogen $$$Selective Estrogen Response Modulators, SERMs 參見:藥理學(pharmacology) $$$Bisphosphonates: inhibit osteoclast $$Bone formation agent |
鑑別診斷(Differential Diagnosis) | |
流行病學(Epidemiology) |
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