商品名(trade name) | |
藥理作用(Pharmacological Effects) | [inhibitors of organic iodine formation (iodination) and coupling (thyroid peroxidase/TPO inhibitor- chemical thyroidectomy) [deodination T4 [block T4 transfer to T3  [thiouracil type drug [can penetrate placental barrier [much safer than methimazole, MMI for pregnancy and during lactation |
用量與用法(Dosage and Usage) | usage ]Medication for12~18 months , but40 ~ 50 % p’t remission ]dosage is variable and depands on T3/FT3 and FT4/FT3 |
適應症(Indications) | {Hyperthyroidism(甲狀腺機能亢進)/thyrotoxicosis(甲狀腺毒症) {prepare hyperthyroid for surgical removal of the gland |
副作用(Side effect) | }overdose: goiter occur due to weak negative feedback }Agranulocytosis }granulocytopenia }allergy:15% }}skin rash |
禁忌/交互作用(Contraindications / interaction) |
Friday, October 11, 2013
propylthiouracil, PTU
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