pancreatic neuroendocrine Carcinoma, panNEC(胰臟神經內分泌癌)

症狀/併發症(symptom/complication)	@usually occur in head of pancreas complication @sometimes hemorrhage
病因(etiology)	|worse differentiated: usually nonfunctional tumor type |large cell: more often, |small cell
檢查/準則(examination/criteria)	#Ki67 index ##>20%:grade 3 pancreatic neuroendocrine tumor=pancreatic neuroendocrine Carcinoma, panNEC(胰臟神經內分泌癌) Ki 67 labelling index in (a) grade I, (b) grade II and (c) grade III meningioma  資料來源：neurologyindia #lack of somatostatin receptors , SSTR #gross: average size is 4 cm #histology ##ill-defined border ##large cell:  size is bigger, hypochromatic ##small cell: nucleolus is not clear but nucleus is hyperchromatic, cytoplasm is really less, (upper small cell; lower larger cell) #neuroendocrine marker: synaptophysin
治療(treatment)
鑑別診斷(Differential Diagnosis)
流行病學(Epidemiology)	+2~3% of pancreatic neuroendocrine neoplasia +1% of malignant pancreatic tumor

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