Sunday, October 20, 2013

pancreatic neuroendocrine tumor, panNET(胰臟神經內分泌腫瘤)

症狀/併發症(symptom/complication)
@size of tumor usually less than 0.5 cm
病因(etiology)
|usually well differentiated,therefore, functional tumor is common
檢查/準則(examination/criteria)
#Ki67 index
##<2%: grade 1 pancreatic neuroendocrine tumor
##2~20%: grade 2 pancreatic neuroendocrine tumor
##>20%:grade 3 pancreatic neuroendocrine tumor=pancreatic neuroendocrine Carcinoma, panNEC(胰臟神經內分泌癌)

Ki 67 labelling index in (a) grade I, (b) grade II and (c) grade III meningioma 
資料來源:neurologyindia
#often have somatostatin receptors,SSTRs, especially SSTR-2 and SSTR-5
#gross: usually whitish-yellow to pinkish-brown, often solid

資料來源:自然期刊
#histology
##uniform cuboidal cells
##eosinophilic cytoplasm
##oval nuclei and distinct border
##Cell arrangement
###trabecular
###gyriform: looks like gyrus
###pseudoglandular: looks like glandular
###solid medullary: stromal sclerosis
###paraganglioma-like: small balls like
#neuroendocrine marker
##synaptophysin: more sensitivity, and often be used

資料來源:springbio
##chromogranin A

資料來源:維基百科
治療(treatment)

鑑別診斷(Differential Diagnosis)

流行病學(Epidemiology)


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