商品名(trade name) | |
藥理作用(Pharmacological Effects) | [hyperpolarization: increase ATP-sensitive K+ channels-->K+ exflux [smooth muscle hard to reach threshold-->vasodialation [Ca2+ influx decrease-->contraction of smooth muscle decrease 參見：平滑肌收縮(Smooth muscle contraction) 參見：平滑肌的興奮(Smooth muscle excitement) [prodrug need Hepatic sulfotransferase metabolize to Minoxidil N-O sulfate [Stimulation of the sympathetic nervous system: negative feedback of hypotension [[Increase heart rate and contractility [[Increase plasma renin activity: combined use with beta adrenergic agonist to prevent renin |
用量與用法(Dosage and Usage) | usage ]Orally ]Urine excretion ]Arterioles >> Venules |
適應症(Indications) | |
副作用(Side effect) | }Increase cardiac output-->Pulmonary hypertension(肺高壓) }hypertrichosis: due to local blood flow increase |
禁忌/交互作用(Contraindications / interaction) |
Wednesday, November 13, 2013
minoxidil
Subscribe to:
Post Comments (Atom)
No comments:
Post a Comment