Monday, November 11, 2013

Na+ channel blockers(鈉離子通道阻斷劑)

商品名(trade name)

藥理作用(Pharmacological Effects)
|this kind of drugs are frequency-dependent, do not block normal sodium channel
 type
|IA: decrease Vmax (O type), I type Na+ channel block, prolong APD (Ix1/K+ channel block): quinidine

資料來源:維基百科
|IB: minimal effect on Vmax, shorten APD (inhibit residual Na+), and I type Na+ channels: lidocaine

資料來源:維基百科
IC: marked inhibition of Vmax (O type), I type Na+ channel block, minimal effect on APD : flecainide
資料來源:維基百科
APD=action potential duration
用量與用法(Dosage and Usage)

適應症(Indications)

副作用(Side effect)

禁忌/交互作用(Contraindications / interaction)

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