商品名(trade name) | generic name &captopril &enalapril &lisinopril &quinapril &ramipril &benazepril &fosinopril &moexipril &perindopril &trandolapril |
藥理作用(Pharmacological Effects) |  [inhibit Angiotensin II and aldosterone synthesis [Bradykinin metabolism decrease-->Prostaglandin synthesis increase→ vasodilation  資料來源：scielo [Kininase II = ACE [Salt and water retention decrease |
用量與用法(Dosage and Usage) | |
適應症(Indications) | |
副作用(Side effect) | }Airway obstruction: bradykinin: Enhance cough reflex }angioedema: promote vasodialation }醛固酮(Aldosterone) synthesis block: hyperkalemia }Angiotensin II formation inhibtion }}efferent vasoconstriction decrease: more blood need to be filtered }}Aggravating renal failure |
禁忌/交互作用(Contraindications / interaction) | Contraindications ?pregnancy: fetal will hypotension or renal failure-->Teratogenic and stillbirth nteraction ?do not use with Angiotensin II Receptor Antagonists, ARBs, that's will cause hypokalemia and relatively low BP |
Wednesday, November 13, 2013
Angiotensin Converting Enzyme Inhibitors, ACEi
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