商品名(trade name) | |
藥理作用(Pharmacological Effects) | [can only stimulate alpha 2 receptor and do not effect on alpha 1 receptor and beta receptor [reduce heart rate and relax capacitance vessels-->stroke volume reduce-->reduce cardiac output (法蘭克-史達林定律(Frank-Starling law)) 參見：腎上腺性接受器(Adrenoceptors) [the effect will be not so well when salt and water retention, and use diuretics can improve this symptom--> pseudotolerance |
用量與用法(Dosage and Usage) | usage ]oral, but high first pass effect ]urine excretion: 6% unchanged ]do not sudden withdrawal, will cause sudden withdrawal symptom |
適應症(Indications) | {Patients with renal insufficiency and pregnant women can still use clonidine {pheochromocytoma diagnosis: tumor do not present negative feedback and keep producing catecholamine |
副作用(Side effect) | }sedation }dry mouth }xerastomia(毛髮乾燥) }postural hypotension(輕微的姿勢性低血壓) |
禁忌/交互作用(Contraindications / interaction) |
Tuesday, November 12, 2013
clonidine
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