Wednesday, November 13, 2013

guanethidine

商品名(trade name)

藥理作用(Pharmacological Effects)
[Depletes catecholamine
[Triphasic response: anesthetize adrenergic fibers and then depletes catecholamine from the motor end plate

資料來源:studyblue
用量與用法(Dosage and Usage)
pharmacokinetics
]Arterioles > Venules > heart > Adrenal medulla
適應症(Indications)

副作用(Side effect)
} Weakness
} Fluid retention
} Diarrhea
} Postural hypotension: guanethidine reduce sympathetic nerve function
} Severe hypertension in patients with pheochromocytoma: due to a period without catecholamine stimulation, and nonadrenergic receptor sensitivity increase
禁忌/交互作用(Contraindications / interaction)

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