methyldopa

商品名(trade name)
藥理作用(Pharmacological Effects)	[Kind of False neurotransmitter  [analogue of dopa at alpha site, can only stimulate alpha 2 receptor and do not effect on alpha 1 receptor and beta receptor 參見：腎上腺性接受器(Adrenoceptors) [[L-tyrosine ⇨ L-dopa ⇨ dopamine ⇨ norepinephrine ⇨ epinephrine [[α-methyldopa ⇨ α-methyldopamine ⇨ α-methylnorepnephrine [reduce peripheral vascular resistance and compensate to increase cardiac output [the effect will be not so well when salt and water retention, and use diuretics can improve this symptom--> pseudotolerance
用量與用法(Dosage and Usage)	usage ]oral, but high first pass effect ]urine excretion
適應症(Indications)	{Patients with renal insufficiency and pregnant women can still use methyldopa
副作用(Side effect)	}Central toxicity }}Depression }}Sleep disturbances }}Headaches }}Inhibit mental acuity and forgetfulness }}Parkinsonian signs }Dry mouth }Impotency }Diarrhea }Immunological abnormalities }}Hemolytic anemia }}Leukopenia; Thrombocytopenia; Red-cell aplasia }Hepatitis: induce hepatitis
禁忌/交互作用(Contraindications / interaction)

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