Monday, November 11, 2013

Lorcainide

商品名(trade name)

藥理作用(Pharmacological Effects)
[O type Na+ channels block--> Na+ influx is relatively slow
[[Vmax decrease
[[prolong ERP
[[minimal effect on APD??
[[conduction decreased of atrium, Purkinje fibers, and ventricle
[[EKG: increase PR interval, widen QRS complex, less effect on QT interval
APD=action potential duration
用量與用法(Dosage and Usage)
usage
]Per os
]IV
適應症(Indications)
[refractory arrhythmia (2nd choice): such as digoxin cause tachycardia
副作用(Side effect)
{caused Hyperaldosteronism(醛固酮過多)=Conn syndrome
{{nausea
{{vomitng
{{anorexia
{{fatigue
{{convulsion
{{confusion
{{lethargy
{{coma
{{death.
禁忌/交互作用(Contraindications / interaction)

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