Monday, November 11, 2013

Metoprolol

商品名(trade name)

藥理作用(Pharmacological Effects)
[beta1 selcetive blocker 
[[c-AMP dependent Ca2+ current decreased
參見:cAMP二級信差(cAMP second messenger)
[[SA and AV node or ectopic automaticity decreased
[[SA and AV node Vmax decreased
[[AV conduction decreased
[[ECG
[[[Prolong PR interval
[[[QT interval is variable
[[[do not effect QRS complex
[analogue to propranolol
用量與用法(Dosage and Usage)

適應症(Indications)
{supraventricular arrhythmia: treat for catecholamine excessive
{hypertension(高血壓) patients
{{heart failure
{{CHD: angina, post MI
{{Hyper-adrenergic tone
{{Under physician’s judgment
副作用(Side effect)
}do not have bronchospasm
參見:腎上腺性接受器(Adrenoceptors)
}acute heart failure: maybe
}bradycardia
}hard to find out hypoglycemia
}impotence
禁忌/交互作用(Contraindications / interaction)

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